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Huntington's disease

Department of Medicine, Division of Medical Science, University of Birmingham, Birmingham B15 2TH, UK

Correspondence: Dr Ramsden D.B.Ramsden{at}bham.ac.uk

The most recent findings in the elucidation of the molecular pathology of Huntington's disease are reviewed. Particular interest has been paid to the role of huntingtin and its associated proteins in excitotoxicity mediated via NMDA and kainate receptors.

Key Words: Huntington's disease • neurodegenerative disorder • Huntingtin • NMDA receptors • kainate receptors

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