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The aetiology of idiopathic Parkinson's disease

Abstract

Agents potentially involved in the aetiology of idiopathic Parkinson's disease are discussed. These include factors regulating dopaminergic neurogenesis (Nurr 1, Ptx-3, and Lmx1b) and related proteins, together with genes involved in familial Parkinson's disease (α synuclein, parkin, and ubiquitin carboxy terminal hydroxylase L1), and endogenous and environmental agents.

  • Parkinson's disease
  • environmental agents
  • transcription factors
  • α synuclein
  • parkin
  • ubiquitin carboxy terminal hydroxylase L1

https://doi.org/10.1136/mp.54.6.369

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