Table 4

K-ras mutations in 118 female patients with cancer of the rectum

Patient	Codon	Mutation		IHC (F-234)
*Second carcinoma after radiotherapy of cervical cancer.
ICH, immunohistochemical staining of formalin fixed, paraffin wax embedded section of tumours with F-234 anti-K-ras antibody; –, < 20% positive nuclei; +, ≥ 20% positive nuclei; NT, not tested.
RE43*	12	GGT → GAT	Gly → Asp	NT
RE78	12	GGT → GAT	Gly → Asp	+
RE86	12	GGT → GAT	Gly → Asp	+
RE108	12	GGT → GAT	Gly → Asp	NT
RE23*	12	GGT → TGT	Gly → Cys	NT
RE112	12	GGT → TGT	Gly → Cys	+
RE126	12	GGT → TGT	Gly → Cys	+
RE58	12	GGT → GTT	Gly → Val	–
RE124	12	GGT → GTT	Gly → Val	+
RE69*	12	GGT → GCT	Gly → Ala	+
RE99*	12	GGT → GCT	Gly → Ala	+
RE36	12	Duplication 3 bp		+
RE38	13	GGC → GAC	Gly → Asp	+
RE82	13	GGC → GAC	Gly → Asp	+
RE2	61	CAA →CAC	Gly → His	+
RE24	61	CAA → CAC	Gly → His	+

p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women

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