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Mol Path 53:307-312 doi:10.1136/mp.53.6.307

Plasminogen activator system, vascular endothelial growth factor, and colorectal cancer progression

Table 2

Differences in plasminogen activator, PAI and uPAR (ng/mg protein), and VEGF (pg/mg protein) values in colorectal tumour and normal tissue samples

Tumour Normal
PAI, plasminogen activator inhibitor; PAR, plasminogen activator receptor; tPA, tissue type plasminogen activator; uPA, urokinase plasminogen activator; VEGF, vascular endothelial growth factor.
Values are expressed as median with the range in parentheses.
*p < 0.0001, Mann Whitney.
uPA 2.3* (0.1–6.7) 0.2 (0–2.6)
tPA 3.3 (0.1–23.8) 6.8* (1.1–37.5)
uPAR 2.2* (0.2–14.0) 0.6 (0.2–4.1)
PAI-1 9.8* (0.2–62.4) 2.0 (0.1–20.7)
PAI-2 1.0 (0–7.3) 0.7 (0–4.7)
VEGF 189* (30–4156.0) 27 (3–108)

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