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Mol Path 54:160-164 doi:10.1136/mp.54.3.160

Loss of sequences on the short arm of chromosome 17 is a late event in squamous carcinoma of the cervix

Table 1

Detection of human papilloma virus (HPV) types and chromosome 17 losses in the 14 patients studied

Patient HPV type Centromere no. HER2/NEU p53 D17S34
*Patients with fluorescence ratios outside the normal range (0.89–1.05).
†This patient showed loss of the centromeric probe with accompanying loss of all three locus specific probes, giving normal ratios.
1 39 2 0.98 0.97 0.95
2 31 4 0.95 0.94 0.57*
3 16 2/4 0.92 0.93 0.82*
4 18 2 1.04 0.97 0.94
5 16 4 0.96 0.94 0.97
6 16 2 0.98 0.98 0.98
7 Neg 1/2† 1.00 0.95 0.94
8 16 2 0.99 0.60* 0.56*
9 Neg 4 0.97 1.00 0.95
10 16 2 0.97 0.97 0.97
11 16 4 0.94 0.97 0.96
12 16 2 1.02 0.96 0.98
13 16 2 0.99 0.98 1.00
14 16 2 0.94 0.96 0.93

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