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Mol Path 54:289-292 doi:10.1136/mp.54.5.289

Calprotectin inhibits matrix metalloproteinases by sequestration of zinc

Table 2

Calprotectin concentrations giving 50% inhibition of matrix metalloproteinase (MMP) activity

Gelatin microwell assay Casein microwell assay
MMP-2 2.8μM
MMP-3 1.4μM
MMP-7 >11μM 1.4μM
MMP-8 0.3μM
MMP-9 5μM
MMP-13 0.5μM

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