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Mol Path 55:1-18 doi:10.1136/mp.55.1.1
  • Review

Haemophilia A and haemophilia B: molecular insights

Table 4

Allele frequencies for several factor IX gene polymorphisms in different ethnic groups

Frequency
Location Name Alleles Whites Japanese Chinese American blacks
Source references: white data,26 Japanese data,6970 Chinese data,347172 American black data.3472–74
5` BamHI + 0.02 0 0.36
0.98 1 0.64
Intron 3 XmnI + 0.29 0 0.01 0.12
0.71 1 0.99 0.88
Intron 3 BamHI + 0.06 0.02 0.13
0.94 0.98 0.87
Intron 4 TaqI + 0.35 0 0.01 0.14
0.65 1 0.99 0.86
Intron 4 MspI + 0.80 1 0 0.61
0.20 0 1 0.39
Exon 6 MnlI + 0.33 0.03 0.11
0.67 0.97 0.89
3` HhaI + 0.61 0.24 0.17 0.57
0.39 0.76 0.83 0.43

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