Treatment of murine breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor decreases the level of plasminogen activator transcripts, inhibits cell growth in vitro, and reduces tumorigenesis in vivo

Table 1

Anchorage independent colony formation by EMT6 murine mammary carcinoma cells carrying an antisense IGF-IR expression plasmid

Treatment	No. of colonies
Triplicate plates were seeded with 1 × 10³ cells each and colonies were counted 14 days later. Each number represents the average of triplicate determinations expressed as mean (SE).
pRcII/IRAS H	0
pRcII/IRAS J	0
pRcII/IRAS O	0
pRcII/CMV	660 (53)

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