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Mol Path 55:262-272 doi:10.1136/mp.55.4.262
  • Original Article

Alterations of the MDV oncogenic regions in an MDV transformed lymphoblastoid cell line

Table 2

Effects of Marek’s disease virus cell lines inoculated into 1 day old B13 chickens

Cell lines No. chickens Date of sacrifice (or death*) Tumour localisation Other disorders
(0) and (1) indicate the absence or presence of tumours, respectively. All inoculations were carried out by intraperitoneal injections of 107 cells. *Chickens were sacrificed at the week indicated but in some cases they died before.
ND, none determined.
T5 inoculated chickens 955 11* (1) Heart Thymic and bursal atrophy
956 11* (0) Normal
957 7* (ND) (ND)
958 11 (0) Normal
959 11 (1) Liver nodes Normal
960 11 (0) Normal
961 11 (1) Ovary Thymic, splenic, and bursal atrophy
962 11 (1) Ovary, liver, rate, and eyes Thymic and splenic atrophy
T5 “contact” chickens 963 11 (1) Heart, lung, liver, and ovary Thymic, splenic, and bursal atrophy
964 11 (1) Ovary Normal
965 11 (1) Ovary, pancreas, liver, and oesophagus (ND)
966 10* (ND) (ND)
967 11 (1) Ovary (ND)
968 11 (0) Normal
Early T9 inoculated chickens 475 6 (1) Testis, nerves Thymic, splenic, and bursal atrophy
476 6 (1) Ovary, lung Thymic, splenic, and bursal atrophy
477 6* (1) Kidney, liver Thymic and bursal atrophy
478 6* (1) Ovary Thymic and bursal atrophy
479 8 (1) Ovary (ND)
480 8 (1) Ovary (ND)
481 8 (1) Skin, nerves, and nodes in the gut (ND)
482 8 (1) Testis, muscle (ND)
483 6 (1) Testis (ND)
Early T9 “contact” chickens 484 6* (ND) (ND)
485 9* (1) Lung, ovary Thymic, splenic, and bursal atrophy
486 9* (1) Ovary Thymic, splenic, and bursal atrophy
487 11* (1) Ovary (ND)
488 13* (1) Ovary (ND)
489 6* (1) Ovary Thymic and bursal atrophy

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