Table 2
Frequency of loss of heterozygosity (LOH), retention (R), microsatellite instability (MSI), and non-informative results because of homozygosity (X) or non-evaluable PCR (–) for seven microsatellites spanning chromosome 13q in 36 BRCA1 related ovarian and fallopian tube carcinomas
| Marker locus | D13S175 13q11 | D13S260 13q12.3 | D13S263 13q14 | D13S312 13q21 | D13S271 13q22–31 | D13S71 13q32 | D13S173 13q32–4 | Total |
|---|---|---|---|---|---|---|---|---|
| LOH | 8 | 9 | 14 | 8 | 9 | 12 | 9 | 69 |
| R | 8 | 10 | 7 | 4 | 4 | 8 | 6 | 47 |
| MSI | 1 | 1 | 2 | 0 | 0 | 2 | 0 | 6 |
| X | 15 | 4 | 6 | 7 | 11 | 6 | 11 | 60 |
| – | 4 | 12 | 7 | 17 | 12 | 8 | 10 | 70 |
| % LOH | 50% | 47% | 67% | 67% | 69% | 60% | 60% | 59% |
