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Mol Path 56:109-115 doi:10.1136/mp.56.2.109
  • Original Article

The novel human MOST-1 (C8orf17) gene exhibits tissue specific expression, maps to chromosome 8q24.2, and is overexpressed/amplified in high grade cancers of the breast and prostate

Table 2

Ratio of MOST-1 expression in grade 1–3 breast cancers to expression seen in the corresponding adjacent normal tissues

Tumour:normal ratio of MOST-1 mRNA (mean (SD))
Breast cancer grade Semiquantitative RT-PCR Real time RT-PCR
The mean ratios and SD values were calculated from semiquantitative and real time reverse transcription polymerase chain rection (RT-PCR) experiments.
1 and 2 0.8370 (0.3781) (n=14) 1.4148 (1.2565) (n=6)
3 1.6874 (1.5545) (n=13) 2.9154 (5.2143) (n=6)

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