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Mol Path 56:313-317 doi:10.1136/mp.56.6.313
  • Original Article

Cell cycle regulation in patients with intestinal metaplasia at the gastro–oesophageal junction

Table 2

Marker expression in the six study groups

Marker Normal SCJ no inflammation Normal SCJ with inflammation BO OAC SSBO IMNSCJ
Mean score (range; percentage + or more).
BO, Barrett’s oesophagus; IMNSCJ, intestinal metaplasia at a normal squamo–columnar junction; OAC, oesophageal adenocarcinoma; SCJ, squamo–columnar junction; SSBO, short segment Barrett’s oesophagus.
p21 0.3 (0–1; 25%) 0.6 (0–2; 57%) 0.3 (0–1; 25%) 0.8 (0–2; 58%) 0.6 (0–2; 50%) 0.5 (0–2; 43%)
p27 0.4 (0–1; 42%) 0.6 (0–1; 64%) 0.3 (0–1; 25%) 1.1 (0–2; 92%) 0.7 (0–2; 60%) 1.0 (0–2; 71%)
p53 0.1 (0–1; 8%) 0.2 (0–1; 21%) 0.1 (0–1; 8%) 1.5 (0–3; 67%) 0.4 (0–1; 40%) 0.5 (0–2; 43%)
Ki67 0.4 (0–1; 42%) 0.9 (0–2; 71%) 0.3 (0–1; 25%) 1.5 (0–3; 83%) 0.6 (0–1; 60%) 0.6 (0–1; 57%)
Cyclin D1 0.5 (0–1; 50%) 0.5 (0–2; 36%) 0.3 (0–2; 18%) 0.7 (0–2; 58%) 0.4 (0–1; 40%) 1.0 (0–2; 79%)
c-erbB-2 0.5 (0–2; 42%) 0.5 (0–1; 46%) 0.9 (0–2; 67%) 1.2 (0–3; 64%) 0.7 (0–2; 50%) 0.8 (0–2; 62%)

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