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Mol Path 56:328-335 doi:10.1136/mp.56.6.328
  • Original Article

Expression of the cell cycle regulatory proteins p34cdc2, p21waf1, and p53 in node negative invasive ductal breast carcinoma

Table 1

Clinical and pathological data of patients (n = 94)

Parameter No. of patients (%)
DFS, disease free survival; NOS, not otherwise specified; OS, overall survival.
Age (years) (median, 55, range, 24–80)
    ⩽50 40 (43)
    >50 54 (57)
Menopausal status
    Premenopausal 35 (37)
    Postmenopausal 57 (61)
    Unknown 2 (2)
Surgical treatment
Partial mastectomy 22 (23)
Total mastectomy 72 (77)
Tumour size
    ⩽2 cm 45 (48)
    >2 and ⩽5 cm 48 (51)
    >5 cm 1 (1)
Tumour grade
    I 21 (22)
    II 38 (41)
    III 35 (37)
Histological type
    Invasive ductal NOS 80 (85)
    Mucinous 5 (5)
    Papillary 3 (3)
    Medullary 2 (2)
    Apocrine 2 (2)
    Metaplastic 1 (1)
    Tubulolobular 1 (1)
Carcinoma in situ
    Absent 31 (33)
    Present (⩽25%) 34 (36)
    Extensive (>25%) 27 (29)
    Unknown 2 (2)
Oestrogen receptor status
    Positive 54 (57)
    Negative 37 (39)
    Unknown 3 (3)
Progesterone receptor status
    Positive 47 (50)
    Negative 46 (49)
    Unknown 1 (1)
Adjuvant treatment
Chemotherapy 55 (59)
Hormonal treatment 87 (93)
Radiotherapy 41 (44)
Outcome
    No evidence of disease 74 (79)
    Relapse 12 (13)
    Death 8 (9)
DFS (months) Median, 69
Range, 12–188
OS (months) Median, 72
Range 22–88

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