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Mol Path 56:342-346 doi:10.1136/mp.56.6.342
  • Original Article

Laminin 5 γ2 chain expression: a marker of early invasiveness in colorectal adenomas

Table 3

Correlations between clinicopathological parameters and laminin 5 γ2 chain expression in 67 colorectal polyps

Laminin 5 expression Ln 5
Number Negative Positive Positive (%) p Value
Data for the laminin 5 positive and negative groups are given as numbers (%); for grading of laminin 5 γ2 expression, see Material and Methods.
*In four polyps, the size and localisation was not defined.
HGD, high grade dysplasia; LGD, low grade dysplasia; NS, not significant.
Sex
    Female 28 24 (86) 4 (14) 14.3 NS
    Male 39 33 (85) 6 (15) 15.4
Differentiation
    LGD 36 31 (86) 5 (14) 13.9 NS
    HGD 16 11 (69) 5 (31) 31.3
Size (mm)*
    ⩽ 5 18 17 (94) 1 (6) 5.6
    6–9 14 14 (100) 0 0
    10–19 16 11 (69) 5 (31) 31.3 0.022
    ⩾ 20 15 11 (73) 4 (27) 26.7
    < 10 32 31 (97) 1 (3) 3.1 0.006
    ⩾ 10 31 22 (71) 9 (29) 29
Localisation*
    Right colon 10 9 (90) 1 (10) 10
    Left colon 26 24 (92) 2 (8) 7.7 NS
    Rectum 27 21 (78) 6 (22) 22.2

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