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Mol Path 2003;56:361 doi:10.1136/mp.56.6.361
  • Echoes

DNA protein crosslinks and p53 expression are important in defining the danger of exposure to formaldehyde

DNA protein crosslinks (DPC) and mutation in the p53 tumour suppressor gene may be causally related and represent steps in the carcinogenicity of formaldehyde (FA). This has important implications for workers exposed to the latter.

Formaldehyde resins are used in producing adhesives for wood, plastics, textile, …